Using Google Trends and Semrush data between 2021 and 2026, the analysis found current UK monthly search volumes of approximately 18,100 for polynucleotides compared with around 8,100 for dermal fillers. 

The report suggests the trend reflects growing public interest in regenerative aesthetic treatments associated with skin quality and collagen stimulation, rather than volumisation alone. 

However, the analysis also noted that dermal fillers continue to demonstrate stronger treatment-intent searches despite increasing awareness of regenerative procedures. 

The findings highlight growing consumer interest in regenerative aesthetics within the UK market, although online search behaviour does not necessarily reflect actual treatment uptake.